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Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.BTK inhibitors, including the commonly used drug ibrutinib, block B cells' signaling pathway. This is helpful for treating B-cell lymphomas because the cancers arise when this signaling pathway ...
The Neutrophil Btk Signalosome Regulates Integrin Activation during ... Zarbock A (2016). Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and ...
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