High-throughput genome-wide screening methods to detect subtle genomic imbalances are extremely important for diagnostic genetics and genomics. Here, we provide a detailed protocol for a ...

Mantle cell lymphoma (MCL) is characterized by t(11;14)(q13;q32), which results in overexpression of CCND1, and is presumed to derive from naive pre-germinal center CD5 + B cells (Seto et al., 1992; ...

infoQuant Ltd brings microarray technology closer to clinical use with its latest release of copy number analysis and interpretation software "oneClickCGH" and "CGH Fusion" for microarray-based ...

Early efforts to examine genomic changes in the clinical setting relied on cytogenetic techniques such as chromosome karyotyping, a widely used approach to examine chromosomes and identify changes ...

Recent advances in gene analysis technology have been remarkable, and many technologies that can be easily introduced in each in-house laboratory have been developed. Especially a comprehensive gene ...

In addition to the surprising revelation that our chromosomes harbor fewer genes than originally predicted, the Human Genome Project also unveiled that all individuals share approximately 99.9% of ...