The 3-4-3, although an unconventional formation to use, can be overpowered in EAFC if you have the correct tactics set.
MLSsoccer.com continues our multi-part series about how to start playing MLS Fantasy Soccer ... switch to a 3-5-2. The other formations available are: 5-4-1, 5-3-2, 5-2-3, 4-5-1, 4-3-3 or 3-4-3 ...
The 4-3-2-1 is the best formation in the old EA FC and FIFA games. The most successful are probably those with five defenders, but these are often not allowed in competitive modes and tournaments.