Keysville is a town in Burke and Jefferson counties in the U.S. state of Georgia. As of the 2020 census, the city's population was 300. The G…Keysville is a town in Burke and Jefferson counties in the U.S. state of Georgia. As of the 2020 census, the city's population was 300. The Georgia General Assembly incorporated Keysville as a town in 1890. In 1933, the government was dissolved although its charter was not revoked. In late 1990, the government was reconstituted.