Respiratory Syncytial Virus: Virology, Reverse Genetics, and ...
WEBHuman RSV exists as two antigenic subgroups, A and B, that exhibit genome-wide sequence divergence (Table 1). The other members of this genus are bovine RSV (BRSV), ovine RSV (ORSV), and pneumonia virus of mice (PVM) (see Table 1 for amino acid sequence relationships).
Respiratory Syncytial Virus whole-genome sequencing identifies …
WEBMay 23, 2016 · Do, L. A. et al. Direct whole-genome deep-sequencing of human respiratory syncytial virus A and B from Vietnamese children identifies distinct patterns of inter- and intra-host evolution.
A Contemporary View of Respiratory Syncytial Virus (RSV) …
WEBMay 21, 2019 · The genomic organization and virion structure of respiratory syncytial virus (RSV) strain A2 are shown with each of the 10 genes color-coded based on their relative functions: Immunomodulatory (light blue), envelope structure (green), surface structures for attachment and entry (red), and replication and genomic stability (dark blue).
Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes.
Genome-wide study of globally distributed respiratory syncytial virus ...
WEBAug 19, 2023 · The molecular evolution of respiratory syncytial virus (RSV) has been demonstrated to be significantly influenced by mutation and recombination in previous studies.
Genomic characterisation of respiratory syncytial virus: a
WEBTo advance our understanding of respiratory syncytial virus (RSV) impact through genomic surveillance, we describe two PCR-based sequencing systems, (i) RSVAB-WGS for generic whole-genome sequencing and (ii) RSVAB-GF, which targets major viral antigens, G and F, and is used as a complement for chall ….
Respiratory syncytial virus B sequence analysis reveals a
WEBFeb 10, 2021 · Respiratory syncytial virus (RSV) is a major cause of respiratory infections and is classified in two main groups, RSV-A and RSV-B, with multiple genotypes within each of them. For RSV-B,...
Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus ...
WEBWe conducted surveillance of respiratory syncytial virus (RSV) genomic sequences for 100 RSV-A and 27 RSV-B specimens collected during November 2022–April 2023 in Arizona, USA. We identified mutations within prefusion …
Next-generation sequencing of human respiratory syncytial virus ...
WEBHuman respiratory syncytial virus (HRSV) is a leading cause of acute respiratory illness in young children worldwide. Whole genome sequencing of HRSV offers enhanced resolution of strain variability for epidemiological surveillance and provides genomic information essential for antiviral and vaccine development.
amplicon-based protocol for whole-genome sequencing of …
WEBFeb 6, 2024 · Abstract. It is convenient to study complete genome sequences of human respiratory syncytial virus (hRSV) for ongoing genomic characterization and identification of highly transmissible or pathogenic variants. Whole genome sequencing of hRSV has been challenging from respiratory tract specimens with low viral loads.
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